Carcinoma of Islets of Langerhans with Hypoglycaemia
نویسندگان
چکیده
منابع مشابه
MONOPHASIC STATE OF INSULIN SECRETION IN ISOLATED RAT ISLETS OF LANGERHANS BY K+, Ca2+ AND GLUCOSE
Isolation of rat islets of Langerhans was carried out by using collagenase and the destruction of exocrine tissue was performed through the injection of Hanks' solution into the common bile duct. The identification of the islets was done by techniques including the use of a stereomicroscope against a black background. Vital staining was done by an injection of neutral red solution through t...
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factor; here according to current concepts the pituitary growth hormone may play an important part. In the case of the "pre-diabetic fathers," the factor of inheritance must be the determining factor. Jackson contends that when a woman gives a history of having had several large babies, the diagnosis of a pre-diabetic state is justified to such an extent that treatment should be started before ...
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Objective(s): Diabetes is a metabolic disease with an increasing prevalence for which finding new and efficient therapeutic approaches has always been a challenge. Preserving integrity and functionality of pancreatic β-cells as the only source of insulin in the body is such a case. To achieve this goal different cellular targets have been proposed among which pancreatic estrogen receptors have ...
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A small-for-dates male infant who developed acute metabolic acidosis shortly after birth had diabetes and died aged 40 hours. At necropsy there was an absence of any recognizable islets of Langerhans though lymphorecticular aggregates were found. This was the fourth child of healthy unrelated parents whose first child, also a male, died at 48 hours under similar circumstances. It is suggested t...
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The clinical results recently reported by the Edmonton group in recipients of allogeneic islet grafts, all of whom achieved at least temporary insulin independence, has rekindled interest in transplantation of islets of Langerhans as a means to cure diabetes. Long-term islet graft survival has been achieved in a non-human primate pre-clinical model with a protocol of T-cell signaling blockade u...
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ژورنال
عنوان ژورنال: BMJ
سال: 1950
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.4660.982